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Consulting and Contract Research 

Biomolecular Integrations, Inc. also serves as a Contract Research Organization (CRO) providing a wide range of consulting and contract research services. Our clients come from academic institutions as well as research hospitals, biotechnology and pharmaceutical industries. Our research team consists of a pool of experts ranging from basic research scientists to clinical and applied researchers.  Major focus areas of our experts include cell biology, molecular biology, protein biochemistry, metabolism, pharmacology and toxicology.  We have experts in pre-clinical drug discovery and development projects. We are able to combine multiple talents, facilities and resources and thus meet almost any custom contract research requirement. Based on specific requirement of a project, we organize and arrange resources from other collaborators yet maintaining confidentiality of the project.

To inquiry with us regarding a Contracted Research Project, either email us at This e-mail address is being protected from spambots. You need JavaScript enabled to view it , call us 501-661-0202, or mail us through Certified Mail at 1900 N. Bryant St., Little Rock, AR 72207 Suite 202. All inquires will be treated with the strictest confidentality.

Our research is based on proof of principle and early concept driven ideas. We believe in value-added quality product output in a timely manner. Therefore, we design our strategy to minimize failure with an ultimate goal of delivering products on time. Thus, we maintain direct contacts with each client and promote active communication between clients, our scientists and administrators. We regard our lab as an extension of our client’s lab where each experiment is designed around client’s specification of the project. Our consulting and contract research expertise include but not limited to.

 

  • Project administration and management
  • Proof of concept, research strategy and study design
  • Conducting actual experimental research, determining feasibility, method development and data collection
  • Data analysis, interpretation and presentation in desirable format
  • Project risk assessment
  • Product safety evaluation
  • Contract research vendor selection
  • Auditing and developing Good Laboratory Practices (GLP) and Standard Operating Procedures (SOPs)
  • Scientific writing and document preparations

 

Major research areas:

  • Protein production and characterization
  • Protein formulations and stability studies
  • Enzyme metabolism and kinetics
  • Peptide design, synthesis and conjugation
  • Antibody production and characterization
  • Antibody conjugation and purification
  • Enzyme assay developments
  • ELISA Assays and Kit developments
  • Protein-protein interaction studies
  • Carbohydrate and lipid metabolism
  • Membrane biology
  • Subcellular fractionation and localization studies
  • Organelle isolation and characterization
  • Immunohistochemistry and immunocytochemistry
  • Vesicular Trafficking
  • Immunofluorescence and light microscopy
  • Gene cloning, expression and characterization
  • cDNA library construction and screening
  • SiRNA, RNAi, gene silencing
  • Yeast two hybrid screening
  • Pharmacology
  • Receptor agonist binding
  • Drug distribution and Pharmacokinetic analysis
  • Screening of bioactive compounds
  • Cell based bioassays
  • Toxicological evaluations
  • Signal Transduction, G-protein coupled mechanisms
  • Intracellular Signaling
  • Second messenger function characterization
  • Lipid mediators, inositol phosphates, protein kinases, phosphatases, cGMP
  • Cancer biology research
  • Cell proliferation, cytotoxicity and apoptosis
  • Bone mineral, histology and morphometry research