Salivary antioxidant enzymes associated to oral toxicity in haematopoietic cell transplantation: An observational analysis
Background: In haematopoietic cell transplantation (HCT), oral mucositis and xerostomia are related to conditioning-related oxidative stress. The perform of salivary antioxidant enzymes in oral toxicity is poorly described. The aim of this analysis was to substantiate the affiliation between salivary antioxidant enzymes and oral mucositis and xerostomia in HCT.
Design: Saliva from autologous and allogeneic HCT victims (n = 77) was chosen sooner than conditioning (T0), in the midst of the neutropenia interval (T1) and after marrow engraftment (T2). Salivary flow into, full salivary proteins, and superoxide dismutase, catalase and glutathione reductase actions had been measured.
Outcomes: There have been no vital variations in salivary flow into, full salivary proteins and catalase on the three HCT time components. Glutathione reductase ranges had been diminished at T1 compared with T0 (P = .013) and T2 (P = .001). Superoxide dismutase ranges had been elevated from T0 to T2 (P = .013). Neither of these enzymes was associated to oral mucositis. Elevated superoxide dismutase ranges had been associated to xerostomia frequency. Ranges of this enzyme moreover confirmed vital correlation with days of xerostomia in T2 (ρ = .40, P = .002).
Conclusions: Salivary antioxidant enzymes modified sooner than and thru early durations after HCT. The rise in salivary superoxide dismutase suggested partial activation of the salivary antioxidant system and was associated to xerostomia.
biomolecularint
Bovine mRNA- decapping enzyme 1B, DCP1B ELISA KIT |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) |
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| MBS641446-5x02mL | MyBiosource | 5x0.2mL | EUR 2975 |
DCP1B (untagged)-Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B) |
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| SC126398 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (AP) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (AP) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (PE) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (PE) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (APC) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (APC) |
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| MBS6291146-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (FITC) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (FITC) |
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| MBS6291148-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (Biotin) |
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| MBS6291147-02mL | MyBiosource | 0.2mL | EUR 980 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (Biotin) |
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Dcp1b (untagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b), (10ug) |
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| MC219240 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1B (GFP-tagged) - Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B) |
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Dcp1b (Myc-DDK-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b) |
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Dcp1b (GFP-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b), (10ug) |
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DCP1B (Myc-DDK-tagged)-Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B) |
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| RC207398 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 405) |
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| MBS6291150-01mL | MyBiosource | 0.1mL | EUR 980 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 405) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 490) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 490) |
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| MBS6291151-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 550) |
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DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 550) |
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| MBS6291152-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 650) |
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| MBS6291153-01mL | MyBiosource | 0.1mL | EUR 980 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 650) |
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| MBS6291153-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 750) |
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| MBS6291154-01mL | MyBiosource | 0.1mL | EUR 980 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (MaxLight 750) |
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| MBS6291154-5x01mL | MyBiosource | 5x0.1mL | EUR 4250 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (Azide free) (HRP) |
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| MBS6291149-02mL | MyBiosource | 0.2mL | EUR 980 |
DCP1B, ID (DCP1B, mRNA-decapping enzyme 1B) (Azide free) (HRP) |
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| MBS6291149-5x02mL | MyBiosource | 5x0.2mL | EUR 4250 |
Lenti ORF clone of Dcp1b (mGFP-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b) |
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Lenti ORF clone of Dcp1b (Myc-DDK-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b) |
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| MR218839L3 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, Dcp1b (GFP-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b), 200ul, >10^7 TU/mL |
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Lenti ORF particles, DCP1B (mGFP-tagged) - Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), 200ul, >10^7 TU/mL |
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Lenti ORF particles, DCP1B (mGFP-tagged) - Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), 200ul, >10^7 TU/mL |
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Lenti ORF particles, Dcp1b (Myc-DDK-tagged) - Mouse DCP1 decapping enzyme homolog b (S. cerevisiae) (Dcp1b), 200ul, >10^7 TU/mL |
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Lenti ORF particles, DCP1B (Myc-DDK tagged) - Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), 200ul, >10^7 TU/mL |
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Lenti ORF particles, DCP1B (Myc-DDK tagged) - Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), 200ul, >10^7 TU/mL |
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| RC207398L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Human mRNA-decapping enzyme 1B (DCP1B) |
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| 1-CSB-YP811635HU | Cusabio |
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Description: Recombinant Human mRNA-decapping enzyme 1B(DCP1B) expressed in Yeast |
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Human mRNA-decapping enzyme 1B (DCP1B) |
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| 1-CSB-CF811635HU | Cusabio |
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Description: Recombinant Human mRNA-decapping enzyme 1B(DCP1B) expressed in in vitro E.coli expression system |
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mRNA-Decapping Enzyme 1B (DCP1B) Antibody |
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| 20-abx111966 | Abbexa |
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mRNA-Decapping Enzyme 1B (DCP1B) Antibody |
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| abx232270-100ug | Abbexa | 100 ug | EUR 610.8 |
mRNA-Decapping Enzyme 1B (DCP1B) Antibody |
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| abx111966-100l | Abbexa | 100 µl | EUR 612.5 |
mRNA-Decapping Enzyme 1B (DCP1B) Antibody |
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| abx232270-100g | Abbexa | 100 µg | EUR 350 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (AP) |
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| MBS6413670-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (AP) |
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| MBS6413670-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (PE) |
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| MBS6413680-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (PE) |
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| MBS6413680-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (APC) |
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| MBS6413671-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (APC) |
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| MBS6413671-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (HRP) |
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| MBS6413674-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (HRP) |
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| MBS6413674-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (FITC) |
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| MBS6413673-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (FITC) |
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| MBS6413673-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
Lenti ORF clone of Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), mGFP tagged |
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| RC207398L2 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), mGFP tagged |
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| RC207398L4 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (Biotin) |
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| MBS6413672-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (Biotin) |
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| MBS6413672-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| CSB-YP811635HU | Cusabio | 6608 mg | Ask for price |
Recombinant Human mRNA-decapping enzyme 1B(DCP1B) |
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| AP78237 | SAB | each | Ask for price |
Recombinant Human mRNA-decapping enzyme 1B(DCP1B) |
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| AP74579 | SAB | each | Ask for price |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| CSB-CF811635HU | Cusabio | 432 mg | Ask for price |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS7053565-002mg | MyBiosource | 0.02mg | EUR 735 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS7053565-01mg | MyBiosource | 0.1mg | EUR 1350 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS7053565-5x01mg | MyBiosource | 5x0.1mg | EUR 5880 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS1370061-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 360 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS1370061-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 610 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS1370061-05mgYeast | MyBiosource | 0.5mg(Yeast) | EUR 1505 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS1370061-5x05mgYeast | MyBiosource | 5x0.5mg(Yeast) | EUR 6565 |
Recombinant Mouse mRNA-decapping enzyme 1B (Dcp1b) |
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| MBS1360933-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1435 |
Recombinant Mouse mRNA-decapping enzyme 1B (Dcp1b) |
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| MBS1360933-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 1125 |
Recombinant Mouse mRNA-decapping enzyme 1B (Dcp1b) |
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| MBS1360933-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 1195 |
Recombinant Mouse mRNA-decapping enzyme 1B (Dcp1b) |
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| MBS1360933-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1355 |
Recombinant Mouse mRNA-decapping enzyme 1B (Dcp1b) |
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| MBS1360933-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1405 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS9424159-002mg | MyBiosource | 0.02mg | EUR 440 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS9424159-01mg | MyBiosource | 0.1mg | EUR 760 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS9424159-05mg | MyBiosource | 0.5mg | EUR 1975 |
Recombinant Human mRNA-decapping enzyme 1B (DCP1B) |
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| MBS9424159-5x05mg | MyBiosource | 5x0.5mg | EUR 8735 |
Lenti ORF clone of Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), Myc-DDK-tagged |
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| RC207398L1 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF clone of Human DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), Myc-DDK-tagged |
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| RC207398L3 | Origene Technologies GmbH | 10 µg | Ask for price |
3`UTR clone of DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B) for miRNA target validation |
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| SC201741 | Origene Technologies GmbH | 10 µg | Ask for price |
Mouse mRNA- decapping enzyme 2, Dcp2 ELISA KIT |
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| ELI-26523m | Nova Lifetech | 96tests | EUR 736 |
Human mRNA- decapping enzyme 2, DCP2 ELISA KIT |
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| ELI-09113h | Nova Lifetech | 96tests | EUR 696 |
Mouse mRNA- decapping enzyme 1A, Dcp1a ELISA KIT |
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| ELI-26330m | Nova Lifetech | 96tests | EUR 736 |
Human mRNA- decapping enzyme 1A, DCP1A ELISA KIT |
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| ELI-47012h | Nova Lifetech | 96tests | EUR 696 |
Human mRNA-Decapping Enzyme 1B (DCP1B) ELISA Kit |
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| abx386810-96tests | Abbexa | 96 tests | EUR 1093.2 |
Mouse mRNA-decapping enzyme 1B (DCP1B) ELISA Kit |
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| abx509838-96tests | Abbexa | 96 tests | EUR 687.5 |
Human mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9338025-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9338025-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9338025-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9338025-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Mouse mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9341841-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Mouse mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9341841-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Mouse mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9341841-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Mouse mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9341841-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Bovine mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9337109-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Bovine mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9337109-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Bovine mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9337109-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Bovine mRNA-decapping enzyme 1B, DCP1B ELISA Kit |
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| MBS9337109-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 405) |
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| MBS6413675-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 405) |
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| MBS6413675-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 490) |
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| MBS6413676-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 490) |
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| MBS6413676-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 550) |
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| MBS6413677-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 550) |
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| MBS6413677-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 650) |
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| MBS6413678-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 650) |
|||
| MBS6413678-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 750) |
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| MBS6413679-01mL | MyBiosource | 0.1mL | EUR 950 |
DCP1B (mRNA-Decapping Enzyme 1B, DCP1, hDcp1b) (MaxLight 750) |
|||
| MBS6413679-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
Recombinant Bovine mRNA-decapping enzyme 1B (DCP1B) , partial |
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| MBS1321205-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Rat Scavenger mRNA- decapping enzyme DcpS, Dcps ELISA KIT |
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| ELI-32404r | Nova Lifetech | 96tests | EUR 756 |
Mouse Scavenger mRNA- decapping enzyme DcpS, Dcps ELISA KIT |
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| ELI-48380m | Nova Lifetech | 96tests | EUR 736 |
Human Scavenger mRNA- decapping enzyme DcpS, DCPS ELISA KIT |
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| ELI-08941h | Nova Lifetech | 96tests | EUR 696 |
Bovine Scavenger mRNA- decapping enzyme DcpS, DCPS ELISA KIT |
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| ELI-26524b | Nova Lifetech | 96tests | EUR 796 |
Recombinant Pongo abelii mRNA-decapping enzyme 1B (DCP1B), partial |
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| MBS1288890-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Dcp1a (GFP-tagged) - Mouse decapping enzyme (Dcp1a) |
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| MG209319 | Origene Technologies GmbH | 10 µg | Ask for price |
Human Decapping Enzyme 2(DCP2)ELISA Kit |
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| QY-E02926 | Qayee Biotechnology | 96T | EUR 433.2 |
Human Decapping Enzyme 2 (DCP2) ELISA Kit |
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| MBS9312948-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human Decapping Enzyme 2 (DCP2) ELISA Kit |
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| MBS9312948-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Decapping Enzyme 2 (DCP2) ELISA Kit |
|||
| MBS9312948-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Decapping Enzyme 2 (DCP2) ELISA Kit |
|||
| MBS9312948-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
DCP2 (untagged)-Human DCP2 decapping enzyme homolog (S. cerevisiae) (DCP2) |
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| SC100774 | Origene Technologies GmbH | 10 µg | Ask for price |
DCPS (untagged)-Human decapping enzyme, scavenger (DCPS) |
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| SC319248 | Origene Technologies GmbH | 10 µg | Ask for price |
Dcp2 (untagged) - Mouse DCP2 decapping enzyme homolog (S. cerevisiae) (Dcp2), (10ug) |
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| MC211089 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP2 (GFP-tagged) - Human DCP2 decapping enzyme homolog (S. cerevisiae) (DCP2) |
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| RG221165 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1A (untagged)-Human DCP1 decapping enzyme homolog A (S. cerevisiae) (DCP1A) |
|||
| SC318001 | Origene Technologies GmbH | 10 µg | Ask for price |
DCP1A (untagged)-Human DCP1 decapping enzyme homolog A (S. cerevisiae) (DCP1A) |
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| SC319488 | Origene Technologies GmbH | 10 µg | Ask for price |
Decapping Enzyme, Scavenger (DCPS) Antibody |
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| 20-abx125746 | Abbexa |
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Decapping Enzyme, Scavenger (DCPS) Antibody |
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| abx029282-400ul | Abbexa | 400 ul | EUR 627.6 |
Decapping Enzyme, Scavenger (DCPS) Antibody |
|||
| abx029282-80l | Abbexa | 80 µl | EUR 343.2 |
Dcp2 (untagged) - Rat decapping mRNA 2 (Dcp2) |
|||
| RN216629 | Origene Technologies GmbH | 10 µg | Ask for price |
Dcp1a (untagged) - Rat decapping mRNA 1A (Dcp1a) |
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| RN216983 | Origene Technologies GmbH | 10 µg | Ask for price |
Dcps (GFP-tagged) - Mouse decapping enzyme, scavenger (Dcps) |
|||
| MG205053 | Origene Technologies GmbH | 10 µg | Ask for price |
DCPS (GFP-tagged) - Human decapping enzyme, scavenger (DCPS) |
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| RG203052 | Origene Technologies GmbH | 10 µg | Ask for price |
Dcps (untagged) - Mouse decapping enzyme, scavenger (Dcps), (10ug) |
|||
| MC203955 | Origene Technologies GmbH | 10 µg | Ask for price |
Tubulin modifying enzymes as objective for the remedy of tau-related illnesses
- Inside the thoughts of victims with Alzheimer’s sickness (AD), the amount and dimension of microtubules (MTs) are significantly and selectively diminished. MTs are involved in quite a lot of cell options, and defects of the microtubular system have emerged as a unifying hypothesis for the heterogeneous and variable medical exhibits of AD. ‘
- MTs orchestrate their fairly a couple of options by the use of the spatiotemporal regulation of the binding of specialised microtubule-associated proteins (MAPs) and molecular motors. Covalent posttranslational modifications (PTMs) on the tubulin C-termini that protrude on the ground of MTs regulate the binding of these effectors.
- In neurons, MAP tau may be very appreciable and its irregular dissociation from MTs throughout the axon, cell mislocalization and hyperphosphorylation, are most important events leading to neuronal dying. Consequently, compounds concentrating on tau phosphorylation or aggregation are at current evaluated nonetheless their medical significance has not been demonstrated On this evaluation, we deal with the rising hyperlink between tubulin PTMs and tau dysfunction. In neurons, extreme ranges of glutamylation and detyrosination profoundly impression the physicochemical properties on the ground of MTs.
- Moreover, in victims with early-onset progressive neurodegeneration, deleterious mutations in enzymes involved in modifying MTs on the ground have simply currently been acknowledged, underscoring the importance of this enzymatic tools in neurology. We postulate that pharmacologically concentrating on the tubulin-modifying enzymes holds promise as therapeutic technique for the remedy of neurodegenerative illnesses.
Organoarsenicals inhibit bacterial peptidoglycan biosynthesis by concentrating on the vital enzymeMurA
Trivalent organoarsenicals similar to methylarsenite (MAs(III)) are considerably further toxic than inorganic arsenate (As(V)) or arsenite (As(III)). In microbial communities MAs(III) reveals vital antimicrobial train. Although MAs(III) and completely different organoarsenicals contribute to the worldwide arsenic biogeocycle, how they exert antibiotic-like properties is mainly unknown. To find out attainable targets of MAs(III), a genomic library of the gram-negative bacterium,
Shewanellaputrefaciens 200, was expressed in Escherichia coli with selection for MAs(III) resistance. One clone contained the S. putrefaciensmurA gene (SpmurA), which catalyzes the first devoted step in peptidoglycan biosynthesis. Overexpression of SpmurA conferred MAs(III) resistance to E. coli.
Purified SpMurA was inhibited by MAs(III), phenylarsenite (PhAs(III)) or the phosphonate antibiotic fosfomycin nonetheless not by inorganic As(III). Fosfomycin inhibits MurA by binding to a conserved residue that corresponds to Cys117 in SpMurA. A C117D mutant was proof in opposition to fosfomycin nonetheless remained delicate to MAs(III), indicating that the two compounds have completely completely different mechanisms of movement. New inhibitors of peptidoglycan biosynthesis are extraordinarily wished as antimicrobial medicine, and organoarsenicals characterize a new house for the occasion of novel compounds for combating the specter of antibiotic resistance.
ECE1 (Endothelin Converting Enzyme 1, ECE) (HRP) |
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| MBS6414917-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (HRP) |
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| MBS6414917-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (FITC) |
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| MBS6414916-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (FITC) |
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| MBS6414916-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (Biotin) |
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| MBS6414915-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (Biotin) |
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| MBS6414915-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 405) |
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| MBS6414918-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 405) |
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| MBS6414918-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 490) |
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| MBS6414919-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 490) |
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| MBS6414919-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 550) |
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| MBS6414920-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 550) |
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| MBS6414920-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 650) |
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| MBS6414921-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 650) |
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| MBS6414921-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 750) |
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| MBS6414922-01mL | MyBiosource | 0.1mL | EUR 950 |
ECE1 (Endothelin Converting Enzyme 1, ECE) (MaxLight 750) |
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| MBS6414922-5x01mL | MyBiosource | 5x0.1mL | EUR 4120 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx103137 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx103138 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx130012 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx145201-100ug | Abbexa | 100 ug | EUR 469.2 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033018-400ul | Abbexa | 400 ul | EUR 627.6 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033018-80l | Abbexa | 80 µl | EUR 343.2 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033019-400ul | Abbexa | 400 ul | EUR 627.6 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033019-80l | Abbexa | 80 µl | EUR 343.2 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033020-400ul | Abbexa | 400 ul | EUR 627.6 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033020-80l | Abbexa | 80 µl | EUR 343.2 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx004310 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx214580 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx214643 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx172239 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| 20-abx320177 | Abbexa |
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Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx130012-100l | Abbexa | 100 µl | EUR 262.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx130012-1ml | Abbexa | 1 ml | EUR 725 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx130012-200l | Abbexa | 200 µl | EUR 337.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx172239-1ml | Abbexa | 1 ml | EUR 712.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033018-400l | Abbexa | 400 µl | EUR 518.75 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033019-400l | Abbexa | 400 µl | EUR 518.75 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx033020-400l | Abbexa | 400 µl | EUR 518.75 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx145201-1096tests | Abbexa | 10 × 96 tests | Ask for price |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx145201-596tests | Abbexa | 5 × 96 tests | Ask for price |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx145201-96tests | Abbexa | 96 tests | EUR 337.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214580-100tests | Abbexa | 100 tests | EUR 350 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214580-200tests | Abbexa | 200 tests | Ask for price |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214580-20tests | Abbexa | 20 tests | EUR 250 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214643-100tests | Abbexa | 100 tests | EUR 350 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214643-200tests | Abbexa | 200 tests | Ask for price |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx214643-20tests | Abbexa | 20 tests | EUR 250 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx320177-100l | Abbexa | 100 µl | EUR 350 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx320177-50l | Abbexa | 50 µl | EUR 237.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx004310-100l | Abbexa | 100 µl | EUR 475 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx004310-20l | Abbexa | 20 µl | EUR 200 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx004310-50l | Abbexa | 50 µl | EUR 325 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103137-100l | Abbexa | 100 µl | EUR 250 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103137-1ml | Abbexa | 1 ml | EUR 675 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103137-200l | Abbexa | 200 µl | EUR 312.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103138-100l | Abbexa | 100 µl | EUR 262.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103138-1ml | Abbexa | 1 ml | EUR 687.5 |
Endothelin Converting Enzyme 1 (ECE1) Antibody |
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| abx103138-200l | Abbexa | 200 µl | EUR 325 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU54158-100ug | Biomatik Corporation | 100ug | EUR 578.6 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU54158-1mg | Biomatik Corporation | 1mg | EUR 2566.2 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU54158-50ug | Biomatik Corporation | 50ug | EUR 465.3 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41273-100ug | Biomatik Corporation | 100ug | EUR 517 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41273-1mg | Biomatik Corporation | 1mg | EUR 2293.2 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41273-50ug | Biomatik Corporation | 50ug | EUR 415.8 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41274-100ug | Biomatik Corporation | 100ug | EUR 554.4 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41274-1mg | Biomatik Corporation | 1mg | EUR 2457 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPU41274-50ug | Biomatik Corporation | 50ug | EUR 445.5 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPA483Hu01 | Cloud-Clone | 10ug | EUR 168 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| 4-RPA483Hu01 | Cloud-Clone |
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Description: Recombinant Human Endothelin Converting Enzyme 1 expressed in: E.coli |
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Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPA483Mu01 | Cloud-Clone | 10ug | EUR 180 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| 4-RPA483Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Endothelin Converting Enzyme 1 expressed in: E.coli |
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Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| RPA483Ra01 | Cloud-Clone | 10ug | EUR 188 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| 4-RPA483Ra01 | Cloud-Clone |
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Description: Recombinant Rat Endothelin Converting Enzyme 1 expressed in: E.coli |
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Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2030000-001mg | MyBiosource | 0.01mg | EUR 175 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2030000-005mg | MyBiosource | 0.05mg | EUR 320 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2030000-01mg | MyBiosource | 0.1mg | EUR 485 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2030000-02mg | MyBiosource | 0.2mg | EUR 600 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2030000-05mg | MyBiosource | 0.5mg | EUR 1135 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009887-001mg | MyBiosource | 0.01mg | EUR 175 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009887-005mg | MyBiosource | 0.05mg | EUR 310 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009887-01mg | MyBiosource | 0.1mg | EUR 470 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009887-02mg | MyBiosource | 0.2mg | EUR 575 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009887-05mg | MyBiosource | 0.5mg | EUR 1090 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009889-001mg | MyBiosource | 0.01mg | EUR 170 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009889-005mg | MyBiosource | 0.05mg | EUR 295 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009889-01mg | MyBiosource | 0.1mg | EUR 445 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009889-02mg | MyBiosource | 0.2mg | EUR 540 |
Recombinant Endothelin Converting Enzyme 1 (ECE1) |
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| MBS2009889-05mg | MyBiosource | 0.5mg | EUR 1025 |
Ece1 (GFP-tagged) - Mouse endothelin converting enzyme 1 (Ece1) |
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| MG210476 | Origene Technologies GmbH | 10 µg | Ask for price |
Rat Endothelin Converting Enzyme 1 (ECE1) Protein |
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| 20-abx168533 | Abbexa |
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Rat Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx168533-1ml | Abbexa | 1 ml | EUR 237.5 |
Ece1 (untagged) - Mouse endothelin converting enzyme 1 (Ece1), (10ug) |
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| MC221329 | Origene Technologies GmbH | 10 µg | Ask for price |
Human Endothelin Converting Enzyme 1 (ECE1) Protein |
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| 20-abx066416 | Abbexa |
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Mouse Endothelin Converting Enzyme 1 (ECE1) Protein |
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| 20-abx066417 | Abbexa |
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Human Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066416-100g | Abbexa | 100 µg | EUR 550 |
Human Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066416-10g | Abbexa | 10 µg | EUR 212.5 |
Human Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066416-50g | Abbexa | 50 µg | EUR 387.5 |
Mouse Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066417-100g | Abbexa | 100 µg | EUR 587.5 |
Mouse Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066417-10g | Abbexa | 10 µg | EUR 225 |
Mouse Endothelin Converting Enzyme 1 (ECE1) Protein |
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| abx066417-50g | Abbexa | 50 µg | EUR 400 |
ECE-1, Recombinant, Mouse (Endothelin Converting Enzyme-1) |
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| MBS638185-001mg | MyBiosource | 0.01mg | EUR 875 |
ECE-1, Recombinant, Mouse (Endothelin Converting Enzyme-1) |
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| MBS638185-5x001mg | MyBiosource | 5x0.01mg | EUR 3720 |
Cow Endothelin Converting Enzyme 1 (ECE1) ELISA Kit |
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| abx521037-96tests | Abbexa | 96 tests | EUR 1093.2 |
Rat Endothelin Converting Enzyme 1 (ECE1) ELISA Kit |
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| abx521040-96tests | Abbexa | 96 tests | EUR 886.8 |
Pig Endothelin Converting Enzyme 1 (ECE1) ELISA Kit |
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| abx361861-96tests | Abbexa | 96 tests | EUR 990 |
ELISA Kit for Endothelin Converting Enzyme 1 (ECE1) |
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| SEA483Hu | Cloud-Clone | 96Т | EUR 630 |